"I wouldn't be surprised if thousands of individuals get left out because of the information gap," added Tinglong Dai, a Johns Hopkins Carey Business School professor who studies operations management and business analytics in health care.
BUCH
Beim Sterben helfen – dürfen wir das?
Beim Sterben helfen – dürfen wir das?
Bettina Schöne-Seifert
Softcover, gebunden.
117 Seiten.
12, 99 Euro.
eBook: 9,99 Euro.
In profunder Kenntnis der langjährigen medizinethischen Debatten zur Sterbehilfe analysiert Bettina Schöne-Seifert die Landschaft der Sterbehilfe-Fragen und -Argumente in dem neuen Band „Beim Sterben helfen – dürfen wir das?“ der Reihe #philosophieorientiert des J.B. Metzler Verlags und verteidigt entschieden eine liberale Position zur Suizidhilfe
Vaccine rollout has largely been left to the states, and with an "isolated and decentralized health system" in the U.S., as Dai put it, people may not know when they're eligible to get their vaccine. And they may have to be proactive in finding where they can get one and in proving that they meet the criteria to be next in line.
In Phase 1a of the vaccine rollout, health care workers and residents of long-term care facilities are prioritized, easy groups to reach because they're in distinct locations, Greene said.
During the next phase, people 75 and older and front-line essential workers should be prioritized,according to recommendations from the CDC's Advisory Committee on Immunization Practices. After that, Phase 1c will include people 65 to 74 and people 16 to 64 who have high-risk medical conditions, along with other essential workers.
"These are groups that are much harder to reach," Greene said.
Dai expects there to be some confusion and inefficiency as distribution continues in late winter and early spring, when supply is still growing and more, but not all, people are eligible to get a vaccine.
"It's going to be a very complicated triage process," he said, adding that it won't be consistent across health care providers.
USA TODAY vaccine panel:The US has nailed the science behind the COVID vaccine. Next up: logistics and trust.
Federal officials with Operation Warp Speed hope that around 50 million people will have received their first of two shots of a COVID-19 vaccine by the end of January, Health and Human Services Secretary Alex Azar said earlier this week.
Two vaccines, one produced by Pfizer and BioNTech and another by Moderna, have already received emergency use authorization from the U.S. Food and Drug Administration. A Phase 3 clinical trial for the Johnson & Johnson vaccine has completed enrollment, and another vaccine candidate from AstraZeneca and Oxford University is expected to follow a few weeks later.
Azar has said the government should have enough supply so that every American whowants a vaccine can get it by summer 2021.
In the middle stages of rollout, state and local public health officials will have a lot of work to do to clearly define and communicate who is eligible, said John Brownstein, chief innovation officer at Boston Children’s Hospital.
"At the state level, there are going to be important nuances in terms of eligibility," Brownstein said.
He thinks that will change. “We’re gradually coming to the realization that Covid-19 is primarily an autoimmune disease that is triggered by a virus,” Icenogle says. “I submit that eventually we’re going to treat these autoimmune processes with some of our big guns.”
coagulation, which is another feature of severe and deadly Covid-19.
So far, there is no published research on rATG or similar heavy-duty transplant drugs for the treatment of Covid-19. “These are very powerful drugs, and there’s a risk you might endanger someone,” Icenogle says. Some doctors have been willing to test out comparatively mild immunosuppressant drugs, and at least one of those — dexamethasone — has worked. But Icenogle says that many in medicine regard the notion of depleting the immune system of a virus-stricken patient as “at least paradoxical, if not crazy.”
He thinks that will change. “We’re gradually coming to the realization that Covid-19 is primarily an autoimmune disease that is triggered by a virus,” Icenogle says. “I submit that eventually we’re going to treat these autoimmune processes with some of our big guns.”
Emory University’s Sanz says he also believes that immune-suppressing drugs, including some that have not yet been tried in people with Covid-19, will prove helpful. “Without any doubt,” he says. “But I think that only some patients will benefit.”
He emphasizes, again and again, that Covid-19 is a heterogeneous disease. It affects different people in different ways. Outside of a vaccine, there is unlikely to be a panacea or a single category of treatment that works for everyone. Still, Sanz says that a better understanding of the disease’s autoimmune facets, coupled with a broader deployment of immune-moderating therapies, could help improve patient outcomes — both in the short and long term.
“I think autoimmunity is part of the story,” Sanz adds. “It’s not the whole story.”
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"I wouldn't be surprised if thousands of individuals get left out because of the information gap," added Tinglong Dai, a Johns Hopkins Carey Business School professor who studies operations management and business analytics in health care.
BUCH
Beim Sterben helfen – dürfen wir das?
Beim Sterben helfen – dürfen wir das?
Bettina Schöne-Seifert
Softcover, gebunden.
117 Seiten.
12, 99 Euro.
eBook: 9,99 Euro.
In profunder Kenntnis der langjährigen medizinethischen Debatten zur Sterbehilfe analysiert Bettina Schöne-Seifert die Landschaft der Sterbehilfe-Fragen und -Argumente in dem neuen Band „Beim Sterben helfen – dürfen wir das?“ der Reihe #philosophieorientiert des J.B. Metzler Verlags und verteidigt entschieden eine liberale Position zur Suizidhilfe
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Vaccine rollout has largely been left to the states, and with an "isolated and decentralized health system" in the U.S., as Dai put it, people may not know when they're eligible to get their vaccine. And they may have to be proactive in finding where they can get one and in proving that they meet the criteria to be next in line.
In Phase 1a of the vaccine rollout, health care workers and residents of long-term care facilities are prioritized, easy groups to reach because they're in distinct locations, Greene said.
During the next phase, people 75 and older and front-line essential workers should be prioritized,according to recommendations from the CDC's Advisory Committee on Immunization Practices. After that, Phase 1c will include people 65 to 74 and people 16 to 64 who have high-risk medical conditions, along with other essential workers.
"These are groups that are much harder to reach," Greene said.
Dai expects there to be some confusion and inefficiency as distribution continues in late winter and early spring, when supply is still growing and more, but not all, people are eligible to get a vaccine.
"It's going to be a very complicated triage process," he said, adding that it won't be consistent across health care providers.
USA TODAY vaccine panel:The US has nailed the science behind the COVID vaccine. Next up: logistics and trust.
Federal officials with Operation Warp Speed hope that around 50 million people will have received their first of two shots of a COVID-19 vaccine by the end of January, Health and Human Services Secretary Alex Azar said earlier this week.
Two vaccines, one produced by Pfizer and BioNTech and another by Moderna, have already received emergency use authorization from the U.S. Food and Drug Administration. A Phase 3 clinical trial for the Johnson & Johnson vaccine has completed enrollment, and another vaccine candidate from AstraZeneca and Oxford University is expected to follow a few weeks later.
Azar has said the government should have enough supply so that every American whowants a vaccine can get it by summer 2021.
In the middle stages of rollout, state and local public health officials will have a lot of work to do to clearly define and communicate who is eligible, said John Brownstein, chief innovation officer at Boston Children’s Hospital.
"At the state level, there are going to be important nuances in terms of eligibility," Brownstein said.
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He thinks that will change. “We’re gradually coming to the realization that Covid-19 is primarily an autoimmune disease that is triggered by a virus,” Icenogle says. “I submit that eventually we’re going to treat these autoimmune processes with some of our big guns.”
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coagulation, which is another feature of severe and deadly Covid-19.
So far, there is no published research on rATG or similar heavy-duty transplant drugs for the treatment of Covid-19. “These are very powerful drugs, and there’s a risk you might endanger someone,” Icenogle says. Some doctors have been willing to test out comparatively mild immunosuppressant drugs, and at least one of those — dexamethasone — has worked. But Icenogle says that many in medicine regard the notion of depleting the immune system of a virus-stricken patient as “at least paradoxical, if not crazy.”
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He thinks that will change. “We’re gradually coming to the realization that Covid-19 is primarily an autoimmune disease that is triggered by a virus,” Icenogle says. “I submit that eventually we’re going to treat these autoimmune processes with some of our big guns.”
Emory University’s Sanz says he also believes that immune-suppressing drugs, including some that have not yet been tried in people with Covid-19, will prove helpful. “Without any doubt,” he says. “But I think that only some patients will benefit.”
He emphasizes, again and again, that Covid-19 is a heterogeneous disease. It affects different people in different ways. Outside of a vaccine, there is unlikely to be a panacea or a single category of treatment that works for everyone. Still, Sanz says that a better understanding of the disease’s autoimmune facets, coupled with a broader deployment of immune-moderating therapies, could help improve patient outcomes — both in the short and long term.
“I think autoimmunity is part of the story,” Sanz adds. “It’s not the whole story.”