https://www.cnet.com/news/fallout-76-revealed-at-e3/

Now, we know a little bit more. Bethesda's Pete Hines just took the stage at Microsoft's Xbox One E3 event to show the game's first trailer, and offer a few details, starting with a big one: Fallout 76 is the biggest game in the franchise yet -- with a world four times larger than Fallout 4. He also revealed the game's timeline, which, just as fans deciphered from existing Fallout lore, is a prequel that takes place earlier than any other game in the franchise yet.

"Set in the hills of West Virginia," Hines said, "You are one of the first to emerge into a very different and untamed wasteland." And indeed -- it is different. Unlike other Fallout games, the wasteland of West Virginia isn't very old, OR very brown. In fact, throughout the trailer, we can see that players will be treated to a vast, gorgeous landscape, spotted with just as much greenery retaking the cities of humanity as destruction and decay.