https://wccftech.com/unresponsive-apps-bug-introduced-by-windows-10-update-kb5005101-fixed/

Microsoft has resolved a bug introduced by Windows 10 update KB5005101 that resulted in apps failing to open for some users. Apps would also become unresponsive or close unexpectedly for devices using Microsoft Exploit Protection Export Address Filtering (EAF). The problem impacted the latest Windows 10 version 21H1, version 20H2, version 2004, version 1909, version 1809, and Windows 10 Enterprise LTSC 2019.

The company explains the issue: