https://thenextweb.com/syndication/2019/10/08/research-bacteria-can-change-shape-inside-humans-to-avoid-antibiotics/

Widespread antibiotic use is largely to blame for the emergence of antibiotic-resistant bacteria, which is currently one of the biggest threats to global health. Not only does antibiotic resistance already cause an estimated 700,000 deaths a year, it’s also made numerous infections, including pneumonia, tuberculosis, and gonorrhea, harder to treat. Without knowing how to stop bacteria from developing antibiotic resistance, it’s predicted that preventable diseases could cause 10m deaths a year by 2050.

Some of the ways that bacteria become resistant to antibiotics are through changes in the bacteria’s genome. For example, bacteria can pump the antibiotics out, or they can break the antibiotics down. They can also stop growing and divide, which makes them difficult to spot for the immune system.