https://www.cnet.com/news/spider-man-far-from-home-new-trailer-spoils-avengers-endgame-opens-up-the-mcu/

Parker is seen avoiding a phone call from Nick Fury (Samuel L. Jackson), much to Hogan's dismay. But as seen in the earlier trailer, Fury and Maria Hill (Cobie Smulders) recruit Parker from his European trip and introduce him to Quentin Beck (Jake Gyllenhaal) -- who is revealed to be from another Earth in a different dimension.

The trailer confirms that there is now an MCU Multiverse, one in which Gyllenhaal's Beck is from another Earth apparently caused by Thanos' snap tearing a hole in the dimension (something we even hinted at coming after Endgame).