DNA Damage from CRISPR Has Been ‘Seriously Underestimated’
https://motherboard.vice.com/en_us/article/a3qv7a/dna-damage-from-crispr-has-been-seriously-underestimated
This article is part of DNA/IDK , a semi-regular column exploring how genetic modification is shaping the future. Follow along here .
When CRISPR was first revealed to the world in 2013, the peril and promise of the revolutionary new gene-editing technology seemed boundless. CRISPR could end hereditary diseases like Huntington’s and cystic fibrosis, but also raised fears of a designer baby boom or another cold war. Yet if one thing was certain, it was that CRISPR worked and was only getting better: In 2014, researchers used CRISPR to cure a disease in an adult animal for the first time, and since then the technology has been used to modify the genetic material in a human embryo, eliminate HIV in mice, improve agriculture, and enhance its delivery mechanism by using nanoparticles instead of viruses.