https://www.sciencedaily.com/releases/2018/05/180522082118.htm

MR and YPLL rose by 21.2 per 100,000 people and more than 700,000 years from 1999 to 2015. If drug mortality rates had remained at 1999 levels and other patterns of mortality had not changed, MRs and YPLL would have declined considerably for NHW men aged 22-56 years and risen only slightly for corresponding women.

"Particularly noteworthy is the rapid rise in lost life years and mortality rates for non-Hispanic white males in their 20s and 30s. These increases are considerably larger than those experienced by corresponding men or women in their 40s and 50s, who have been the focus of earlier analyses," explained Christopher J. Ruhm, PhD, Frank Batten School of Leadership and Public Policy, University of Virginia, Charlottesville, VA, USA. He points out that focusing on whites in their 40s and 50s missed important components of MR and YPLL growth.