https://www.sciencedaily.com/releases/2022/04/220401141340.htm

Korber, Fischer, Yoon and Theiler are members of a rarified team that the National Institute of Allergy and Infectious Diseases assembled in January 2021, drawing on experts from around the world who specialize in relevant research fields such as viruses, the immune system, vaccines, epidemiology, structural biology, bioinformatics, virus genetics, and evolution. The team is called SAVE, for SARS-CoV-2 Assessment of Viral Evolution.

As noted in the Nature paper, the authors state, "This effort was designed to provide a real-time risk assessment of SARS-CoV-2 variants potentially impacting transmission, virulence, and resistance to convalescent and vaccine-induced immunity. The SAVE program serves as a critical data-generating component of the United States Government SARS-CoV-2 Interagency Group to assess implications of SARS-CoV-2 variants on diagnostics, vaccines and therapeutics and for communicating public health risk."