https://www.sciencedaily.com/releases/2021/10/211004143745.htm > Although the reduction in the number of opioid prescriptions issued by individual GPs was small, when aggregated together they had a large effect. > The campaign was trialled in West Yorkshire and the researchers say over a year, it resulted in 15,000 fewer patients being given opioids -- and a net saving to the NHS of £700,000. If it were replicated across the UK, it could lead to 406,000 fewer patients taking opioid medications.