Researchers Map Structure of Coronavirus “Spike” Protein

Researchers Map Structure of Coronavirus “Spike” Protein

4 years ago
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https://www.scientificamerican.com/article/researchers-map-structure-of-coronavirus-spike-protein/

Researchers worldwide are racing to develop potential vaccines and drugs to fight the new coronavirus, called SARS-Cov-2.  Now, a group of researchers has figured out the molecular structure of a key protein that the coronavirus uses to invade human cells, potentially opening the door to the development of a vaccine, according to new findings.

Previous research revealed that coronaviruses invade cells through so-called “spike” proteins, but those proteins take on different shapes in different coronaviruses. Figuring out the shape of the spike protein in SARS-Cov-2 is the key to figuring out how to target the virus, said Jason McLellan, senior author of the study and an associate professor of molecular biosciences at the University of Texas at Austin.