https://phys.org/news/2018-11-synthetic-molecule-invades-double-stranded-dna.html

"Since the double-helical structure of DNA was first elucidated by Watson and Crick, scientists have been trying to design molecules that can bind to DNA and allow one to control the flow of genetic information," said Ly. "This is the first bifacial molecule that can invade double-stranded DNA or RNA under biologically relevant conditions."

DNA, which contains all of an organism's genetic information, is made up of two strands of nucleotides. The nucleotides connect with each other using hydrogen bonds, forming a helical chain of Watson-Crick base pairs. While these base pairs provide a relatively simple code to our genetic information, getting into the double helix to change the code is difficult due to the strong bonds between the base-pairs.