http://www.spokesman.com/stories/2018/oct/30/nez-perce-smoked-low-nicotine-variety-of-tobacco-b/

Nez Perce Indians grew and smoked tobacco long before white traders and settlers arrived in the Pacific Northwest, new research from Washington State University has revealed.

By testing stone pipes for nicotine residue, the researchers determined the Nez Perce were cultivating wild strains of tobacco 1,200 years ago in the warm, dry climate along the Snake River.