https://phys.org/news/2018-10-platform-based-biology-nanotechnology-mrna.html

Over the past few years, lipid carriers encapsulating messenger RNAs (mRNAs) have been shown to be extremely useful in altering the protein expressions for a host of diseases. But directing this information to specific cells has remained a major challenge.

"In our new research, we utilized mRNA-loaded carriers—nanovehicles carrying a set of genetic instructions via a biological platform called ASSET—to target the genetic instructions of an anti-inflammatory protein in immune cells," says Prof. Peer. "We were able to demonstrate that selective anti-inflammatory protein in the target cells resulted in reduced symptoms and disease severity in colitis.