Mycoplasma genitalium's cell adhesion mechanism revealed

Mycoplasma genitalium's cell adhesion mechanism revealed

6 years ago
Anonymous $ZPWJA6-QD2

https://phys.org/news/2018-10-mycoplasma-genitalium-cell-adhesion-mechanism.html

Mgen is an emerging pathogen responsible for several infectious genitourinary disorders. In men, it is the most common cause of urethritis (15-20%) while in women, it has been associated with cervicitis, pelvic inflammatory disease (PID), premature birth and spontaneous abortions.

So far, it was known that adherence to the genitourinary tract was possible thanks to proteins known as adhesins, which recognise specific cell surface receptors. In the case of Mgen, these cell receptors are generically known as sialic acids. Other important pathogens such as the influenza virus also use sialic acids to adhere to cells.