New enzyme discovery may help improve drugs against cancer, diabetes and obesity

New enzyme discovery may help improve drugs against cancer, diabetes and obesity

6 years ago
Anonymous $RBasgWKaIV

https://phys.org/news/2018-07-enzyme-discovery-drugs-cancer-diabetes.html

A number of drugs that target a group of proteins—the so-called HDAC enzymes—have attracted significant attention in recent years from researchers and drug developers, because they contribute to the development of resistance towards cancer treatments. New research has demonstrated that they also play a crucial role in a whole range of other diseases that are due to dysregulation of human genes.

An organic chemistry research team at the Faculty of Health and Medical Sciences, University of Copenhagen, has been investigating all the 11 HDAC enzymes expressed in human cells to develop specific molecules that can bind to the enzymes and block their activity in the body.