Breakthrough in industrial CO2 usage
https://phys.org/news/2018-07-breakthrough-industrial-co2-usage.html
"Based on the idea that methionine in microorganisms is degraded by enzymes to methional with the release of CO2, we tried to reverse this process," explains Professor Arne Skerra from the Department of Biological Chemistry at TUM, "because every chemical reaction is in principle reversible, while often only with the extensive use of energy and pressure." Skerra participated in the call for proposals with this idea, and Evonik awarded the concept and supported the project.
Supported by postdoctoral researcher Lukas Eisoldt, Skerra began to determine the parameters for the manufacturing process and for producing the necessary biocatalysts (enzymes). The scientists conducted initial experiments and determined the CO2 pressure which would be needed to produce methionine from methional in a biocatalytic process. Surprisingly, an unexpectedly high yield resulted even at a relatively low pressure—approximately corresponding to the one in a car tire of approximately two bars. Based upon the achievements after just one year, Evonik extended the funding, and now the team, reinforced by the Ph.D. student Julia Martin, investigated the biochemical background of the reaction and optimized the enzymes involved using protein engineering.