NIST builds statistical foundation for next-generation forensic DNA profiling

NIST builds statistical foundation for next-generation forensic DNA profiling

6 years ago
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https://phys.org/news/2018-07-nist-statistical-foundation-next-generation-forensic.html

"If you're working criminal cases, you need to be able to generate match statistics," said Katherine Gettings, the NIST biologist who led the study. "The data we've published will make it possible for labs that use NGS to generate those statistics."

To generate a DNA profile, forensic labs analyze sections of DNA, called genetic markers, where the genetic code repeats itself, like a word typed over and over again. Those sections are called short tandem repeats, or STRs, and the number of repeats at each marker varies from person to person. The analyst doesn't actually read the genetic sequence inside those markers, but just counts the number of repeats at each one. That yields a series of numbers that, like a long social security number, can be used to identify a person.