Cell Studio: Serious games for immunology

Cell Studio: Serious games for immunology

6 years ago
Anonymous $hM_jrxqbr-

https://phys.org/news/2018-07-cell-studio-games-immunology.html

Users can feed biological data about an experimental system, run it in real-time and watch the simulation play out in 3-D, while interacting with it as intended. Rules of the simulation can be set by the user so that cells can respond to biological events, which include molecular secretions, changes to membrane protein expression, proliferation cues (mitosis) and apoptosis. Users can stop the experiment, change viewpoint, rewind or intervene by injecting molecules of any kind while the experiment runs. Additionally, while the simulation runs, numerical data becomes available in real-time via FACS plot displays, demonstrating receptor distribution on a monoclonal cell population and quantifying the number of cells in each monoclonal population as classic examples.

The front-end (user-interface) of the game-like simulation allows users to assign rules and visualize its run, built in to the Unity 3-D game engine using the Mega-Fiers Unity package. Cell Studio is based on a 'hybrid' biological modeling paradigm, which deconstructs a system to its constituent entities, assigning each cell or entity as an agent capable of making its own decision based on its local environment, while allowing user interaction with the simulation during the run.