New materials improve delivery of therapeutic messenger RNA
https://phys.org/news/2018-07-materials-delivery-therapeutic-messenger-rna.html
Because mRNA molecules are so large, researchers have had difficulty designing ways to efficiently get them inside cells. It has also been a challenge to deliver mRNA to specific organs in the body. The new MIT approach, which involves packaging mRNA into polymers called amino-polyesters, addresses both of those obstacles.
"We are excited by the potential of these formulations to deliver mRNA in a safe and effective manner," says Daniel Anderson, an associate professor in MIT's Department of Chemical Engineering and a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science (IMES).