https://wccftech.com/cyberpunk-2077-pc-save-filed-corruption-crafting/

Cyberpunk 2077 is a glitchy game on all platforms, that’s been well-established, but most of the bugs can be navigated without too much trouble. Unfortunately, some PC players are experiencing a more serious issue that can irreversibly corrupt your save file. Thankfully, it would seem there is a way around it.

First reported by users on the CD Projekt Red forums, it seems Cyberpunk 2077 save files will become corrupted and unreadable if their file size grows over 8MB (or 8192kb to be exact). Now, most people’s save files probably won’t get that large, but having a ton of stuff in your inventory can cause its size to bloat up. As a result, players who are really into the crafting aspect of Cyberpunk 2077 are the ones running into save file trouble.