https://wccftech.com/microsoft-flight-simulator-to-get-directx-12-improvements-and-dlss-support-soon/

Microsoft’s Flight Simulator is one of those games that are exactly what they are at face value; it’s a game meant to simulate flying in various aircraft with the power of the ACE Engine, used in games like Forza Horizon 4. The game has a very realistic and beautiful aesthetic and is meant to really capture the essence of flying aircraft.

Currently, the game runs with DirectX12 and has minimal issue doing so, at that. There is not any DLSS support at the moment. However, the team at Asobo knows this, and actually addressed it in a Q&A live stream recently. Asobo plans to add DLSS support soon, as well as various improvements to the DirectX12 functionality of the game.