http://www.pcgamer.com/destiny-2-on-the-pc-will-use-blizzards-global-play-region-locking/

With the Destiny 2 early access PC beta set to get underway today for those who've pre-ordered, Bungie has clarified how the game's region system will work. Because the game runs through Blizzard's Battle.net client instead of Steam, it will make use of the same Global Play system as other Blizzard games, such as Overwatch and Hearthstone: Players will have the ability to select which region they want to play in, but will only be able to see games and play with people who are also in that region. 

"When players launch Destiny 2 from the Blizzard desktop application, they will have the option to select their region of play. If the player takes no action to change their region, it will match the default region of the player's Blizzard account," the help page states. "Players who wish to change their Blizzard region may do so by closing the Destiny 2 application, visiting the Destiny 2 landing page in the Blizzard desktop application, and selecting their desired region from the drop down above 'Play'."