https://wccftech.com/cyberpunk-2077-side-quests/

Like The Witcher 3, Cyberpunk 2077 is going to be a huge RPG where players will be able to take on and complete a variety of quests that are not required to advance the plot. Despite being side-quests, it seems like they may have an influence on the main story.

In a recent interview, Cyberpunk 2077 Level Designer Miles Tost talked about side-quests, confirming that they main have some influence on the main story, as they will still be connected to the world and will elaborate on parts of it.