https://www.gamespot.com/articles/fallout-76s-solution-to-dealing-with-griefers-is-b/1100-6461102/

Bethesda has discussed how Fallout 76 will deal with griefers, namely players that are intent on attacking and killing others, even when their target isn't interested in player versus player combat. As discussed during the game's QuakeCon 2018 panel by game director Todd Howard, Bethesda decided to turn griefers into content for other players by giving them a taste of their own medicine.

"We want this element of danger, without griefing," said Howard, who continued on to explain that when you shoot someone you do a little bit of damage. He equated this action to lightly slapping someone in a bar to see if they want to fight. The other player can choose to ignore this slap or engage, and if it's the latter you start doing full damage.