https://www.pcgamer.com/ghost-recon-wildlands-gets-a-new-permadeath-ghost-mode-later-this-month/

Ghost Recon: Wildlands is getting a new PvE mode called Ghost Mode, and if you felt like the vanilla game didn't demand quiet, tactical play, this will hopefully make up for it. The PvE mode is basically a new difficulty for the campaign, and features permadeath, friendly fire, as well as a one-weapon limit on your loadout. This loadout can only be  swapped out at ammo boxes littered throughout the world, or you can pick up the weapons of fallen enemies.

Meanwhile, reloading your weapon before the clip is depleted will see you lose those remaining bullets.  Oh, and if you die, you lose everything and must restart the game. So yeah, you have to be tactical. And yet, there are still five difficulty levels within Ghost Mode, ranging Arcade through to Extreme and 'Tier 1'.