https://www.pcgamer.com/madman-beats-fallout-new-vegas-on-max-difficulty-without-dying-or-killing-anyone/

I've seen people beat Fallout: New Vegas without killing anyone. I've seen people beat it without dying. And I've seen people beat it without firing a single gun. But I've never seen someone beat it on the highest difficulty setting, with both hardcore mode and permadeath enabled, without killing anyone, without dying, without the help of any companions, and without using any weapons apart from boxing gloves—until today, that is. Because Youtuber Rhetam did exactly that, not only finishing the main story via the NCR path but also clearing every sidequest in the game despite the harsh rules he set for himself. 

Rhetam started his bonkers challenge run, which you can watch in full on his Youtube channel, back in March 2017. He posted the final episode, episode 19, yesterday, July 10. After more than a year of careful planning and even more careful execution, he finished Fallout: New Vegas at level 26 with his Sneak, Speech and Unarmed skills all at level 100.