https://www.pcgamer.com/kingdom-come-deliverance-adds-survival-style-hardcore-mode/

Kingdom Come: Deliverance has rolled out a new Hardcore mode, alongside its latest 1.6 patch. And if you thought survival in 13th century Bohemia was challenging before, trying staying alive minus fast travel, quick saving and compass indicators. 

Then try taking on board two permanent negative perks—such is a requirement of the new mode. Ailments cover everything from Nightmares that inflict short-term debuffs, to Tapeworms that heighten your appetite, and Claustrophobia that lowers attacks whenever your helmet visor is closed.