https://www.businesswire.com/news/home/20180611005707/en/

VALENCIA, Calif.--(BUSINESS WIRE)--Jun 11, 2018--SetPoint Medical, a clinical-stage biomedical technology company developing bioelectronic therapy for chronic inflammatory diseases, announced the presentation of positive clinical results from the company’s proof-of-concept study using bioelectronic medicine to treat Crohn’s disease, a debilitating condition caused by inflammation of the gastrointestinal tract. The data, presented in a poster session at the Digestive Disease Week meeting in Washington, D.C., showed that over 60% of patients achieved significant reductions in their disease activity as assessed by the Crohn’s Disease Activity Index (CDAI).

This open-label study was conducted at five European centers and included 16 patients with moderate to severe Crohn’s disease with inadequate responses to tumor necrosis factor (TNF) antagonist drugs and other non-TNF targeted biologic agents. All patients were implanted with a vagus nerve stimulating device to deliver digital doses of electricity designed to activate the cholinergic anti-inflammatory reflex to produce a systemic immunorestorative effect.