https://phys.org/news/2019-01-gene-african-salmonella.html > Invasive nontyphoidal Salmonellosis (iNTS) occurs when Salmonella bacteria, which normally cause gastrointestinal illness, enter the bloodstream and spread through the human body. The African iNTS epidemic is caused by a variant of Salmonella Typhimurium (ST313) that is resistant to antibiotics and generally affects individuals with immune systems weakened by malaria or HIV. > "Although the genomes of African and global S. Typhimurium are 95% identical, the remaining 5% is very different," explains study author Dr. Rocío Canals Alvarez. "Most of these differences do not cause changes in gene expression, but we need to identify the genetic alterations that affect gene expression and could influence the outcome of a bacterial infection in humans."